| 1. | Chen HW, Ferrando, AA, White MG, Dennis RA, Xie JJ, Pauly M, Park S, Bartter T, Dunn MA, Ruiz-Margain A, Kim WR, Duarte-Rojo A. Home-based physical activity & diet intervention to improve physical function in advanced liver disease: A randomized pilot trial. Dig Dis Sci 2020 (In Press). | 2020 |
| 2. | Lin, F-P., Ferrando, AA, Dunn, M., Kim, W.R., Duarte-Rojo, A. Exercise-induced hyperammonemia does not precipitate overt hepatic encephalopathy. Hepatology 2020 (In Press). | 2020 |
| 3. | Kim, I-Y., Park, S., Smeets, E., Schutzler, S., Azhar, G., Wei, J., Ferrando, AA, Wolfe, R.R. Consumption of a specially-formulated mixture of essential amino acids promotes gain in whole body protein to a greater extent than a complete meal replacement in older women with heart failure. Nutrients 2019 11(6). | 2019 |
| 4. | Church, D., Gwin, J.A., Wolfe, R.R., Pasiakos, S.M., Ferrando, AA. Mitigation of Muscle Loss in the Stressed Physiology: Military Relevance. Nutrients; 2019:11 (8), 1703. | 2019 |
| 5. | Parry, HA, C. Mobley, B, Mumford, PW, Romero, MA, Roberson, PA, Haun, CT, Zhang, Y, Zempleni, J, Ferrando, AA, Vechetti, IJ, McCarthy, JJ, Young, KC, Roberts, MD, Kavazis, AN. Effects of bovine milk exosome depletion on skeletal muscle biomarkers in rapidly maturing rats. Frontiers in Physiology. 2019 10:436. | 2019 |
| 6. | Wolfe, R.R., Park, S., Kim, I-Y., Starck, C., Marquis, B., Ferrando AA, Moughan, PJ. Quantifying the contribution of dietary protein to whole body protein kinetics: examination of the intrinsically-labeled proteins method. Am J Physiol Endo Metab. 2019 317: E74-E84 | 2019 |
| 7. | Wolfe, R.R., Park, S., Kim, I-Y., Starck, C., Marquis, B., Ferrando AA, Moughan, PJ. Reply to Letter to the Editor: “The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation”. Am J Physiol Endocrinol Metab. 2019 Sep 1;317(3): E435. | 2019 |
| 8. | Kim, I-Y., Park, S., Smeets, E., Schutzler, S., Azhar, G., Wei, J., Ferrando, AA, Wolfe, R.R. Consumption of a specially-formulated mixture of essential amino acids promotes gain in whole body protein to a greater extent than a complete meal replacement in older women with heart failure. Nutrients 2019 11(6). | 2019 |
| 9. | Church, D., Pasiakos, S.M., Wolfe, R.R., Ferrando, A.A. Acute testosterone administration does not affect muscle anabolism. Nutrition and Metabolism 2019 16:56. | 2019 |
| 10. | Margolis, L., Wilson, M., Whitney, C., Carrigan, C., Murphy, N., Radcliffe, P., Gwinn, J., Church, D., Wolfe, R., Ferrando, AA, Young, A., Pasiakos, S. Acute hypoxia suppresses exogenous glucose oxidation, glucose turnover, and metabolic clearance rate during steady-state aerobic exercise. Metabolism 2019 (Epub). Compton, M. Denise. February 2019. Alcohol and Substance Use in Older Adults. The Journal of the Arkansas Medical Society | 2019 |
| 11. | Ayyadevara S, Ganne A, Hendrix RD, Balasubramaniam MS, Shmookler Reis RJ, Barger, SW. Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease. J Neurosci Methods 319:40-46, 2019. PMID 30412730 DOI: 10.1016/j.neumeth.2018.11.005 | 2019 |
| 12. | Tarkhov AE, Alla R, Ayyadevara S, Pyatnitskiy M, Menshikov LI, Shmookler Reis RJ, Fedichev PO. A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories. Sci Rep 2019, 9: 7368. doi.org/10.1038/s41598-019-43075-z 1 | 2019 |
| 13. | Balasubramaniam MS, Ayyadevara S, Ganne A, Kakraba S, Du X, Crooks PA, Griffin ST, Shmookler Reis RJ. Aggregate interactome based on protein-crosslinking interfaces predicts drug targets to limit aggregation in neurodegenerative diseases. iScience 2019 DOI: 10.1016/j.isci.2019.09.026 | 2019 |
| 14. | Kakraba S, Ayyadevara S, Reddy Penthala N, Balasubramaniam S, Ganne A, Liu L, Alla R, Bommagani SB, Barger SW, Griffin WST, Crooks PA, and Shmookler Reis RJ. A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer’s Disease. Front. Mol. Neurosci., 12 December 2019 DOI: 10.3389/fnmol.2019.00310 | 2019 |
| 15. | Mendiratta P, Wei JY, Dayama N, Li X. Outcomes for Hospitalized Older Adults with Down syndrome in the United States. J Alzheimer’s Disease 2019: 66(1):1-10. | 2019 |
| 16. | Kim, I.; Park, S.; Smeets, E.T.H.C.; Schutzler, S.; Azhar, G.; Wei, J.Y.; Ferrando, A.A.; Wolfe, R.R. Consumption of a Specially-Formulated Mixture of Essential Amino Acids Promotes Gain in Whole-Body Protein to a Greater Extent than a Complete Meal Replacement in Older Women with Heart Failure. Nutrients 2019, 11, 1360. | 2019 |
| 17. | Mendiratta P, Azhar G, Dayama,N, Wei JY, Prodhan P, Prodhan P. Bariatric Procedures in Older Adults in the United States: Analysis of a Multicenter Database. Geriatrics 04/2019; 4(2):32. | 2019 |
| 18. | Newman JC1, Sokoloski JL2, Robbins PD3, Niedernhofer LJ3, Reed MJ4, Wei J5, Austad SN6, Barzilai N7,8,9, Cohen HJ10, Kuchel GA11, Kirkland JL2, Pignolo RJ2. Creating the Next Generation of Translational Geroscientists. J Am Geriatr Soc. 2019 Jul 9. doi: 10.1111/jgs.16055 | 2019 |
| 19. | Mendiratta P , Dayama,N, Wei JY, Prodhan P, Parthak Prodhan. Status Epilepticus among Older Adults in the United States. Geriatrics 2019; Jul 23;4(3). pii: E45. doi: 10.3390/geriatrics4030045. | 2019 |
| 20. | Pinto Miranda V, Munoz Mendoza J, Mendiratta P, Azhar G, Wei J.Y. His lungs sound horrible. 2019 Annual Scientific Meeting of the American Geriatrics Society, Portland, Oregon – 2019 | 2019 |
| 21. | Pinto Miranda V, Munoz Mendoza J, Mendiratta P, Azhar G, Wei J.Y. I don’t know how to keep this patient out of the hospital! 2019 Annual Scientific Meeting of the American Geriatrics Society, Portland, Oregon – 2019 | 2019 |
| 22. | Harris M, DeClerk L, Schafer P, Hutchison L, Kelly MA, deGravelles P, Mendiratta P.Innovative implementation of video-enabled remote standardized patient simulation on interprofessional competencies and late-life depression screening. J Res Interprof PractEdu. (under review) June 2019. | 2019 |
| 23. | Padala KP, Mendiratta P, Lensing SY, Wei JY, Sullivan DH, Padala PR. Are Medical Students Well Trained for Interdisciplinary Format of Medical Education? Journal of American Geriatric society June 2019 (under review) | 2019 |
| 24. | Mendiratta P. Clinical Frailty Score. Statpearls, 2019 (accepted) | 2019 |
| 25. | Mendiratta P, Dayama N, Azhar G, Wei JY, Prodhan P. Status Epilepticus among older adults in the United States. Geriatrics (Basel). 2019; 23;4;E45. | 2019 |
| 26. | Mendiratta P, Dayama N, Azhar G, Prodhan P, Wei JY. Bariatric procedures in older adults in the United States: Analysis of a multicenter database. Geriatrics (Basel). 2019;4, E32. | 2019 |
| 27. | Balasubramaniam M, Parcon P, Bose C, Liu L, Jones R, Farlow MR, Mrak R , Griffin WS. IL-1Β influences autophagy by mediating upregulation of parkin and parkin neddylation in cell culture and i n animal models, mimicking the pattern seen in brains of Alzheimer patients (Dec 27, 2019 Journal ofNeuroinflammation) | 2019 |
| 28. | Balasubramaniam M, Ayyadevara S, Kakraba S, Penthala NR, Ganne A, Du X, Crooks PA, Shmookler Reis RJ. Aggregate interactome and neural network based on protein-crosslinking interfaces predicts drug targets to limit aggregation in neurodegenerative diseases (Cell- press iScience, 2019, Oct 25) | 2019 |
| 29. | Bommagani, S. Penthala NR, Balasubramaniam M, Kuravi S, Caldas-Lopes E, Guzman ML, Balusu R, Crooks PA. A novel tetrazole analogue of resveratrol is a potent anticancer agent. Bioorg Med Chem Lett 29, 172-178, doi:10.1016/j.bmcl.2018.12.006(2019). | 2019 |
| 30. | Bhavya S. G, Rajashekarappa S, Prasanna D. Revanasiddappa, Vivek Chandramohan, Balasubramaniam M, Vardhineni Teja Priya. Structural insights of metallo-beta-lactamase revealed an effective way of inhibition of enzyme by natural inhibitors (in press Journal of Biomolecular Structure and Dynamics, 2019 Sep 23). | 2019 |
| 31. | Lakkaniga R, Balasubramaniam M, Frett B, Li HL. Structural characterization of the Aurora Kinase B ‘DFG-flip’ and insights into subtype selectivity of Barasertib (Dec 18, 2019,AAPS) | 2019 |
| 32. | Duarte-Rojo, A, Ruiz-Margain, A, Montano-Loza, A, Macais-Rodriguez, R, Ferrando AA, Kim, WR. Exercise and physical activity for patients with ESLD: improving functional status and sarcopenia while on the transplant waitlist. Liver Transplantation; 2018 Jan; 24(1):122-139. | 2018 |
| 33. | Parcon PA, Balasubramaniam M, Ayyadevara S, Jones RA, Liu L, Shmookler Reis RJ, Barger SW, Mrak RE, Griffin WST. Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs. Alzheimers Dement 14: 230‒242, 2018. PMID: 28945989. DOI: 10.1016/j.jalz.2017.07.754. | 2018 |
| 34. | Kiaei M, Balasubramaniam M, Govind Kumar V, Shmookler Reis RJ, Moradi M, Varughese KI. ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation. Sci Rep 8: 13102, 2018. DOI: 10.1038/s41598-018-31199-7. PMID: 30166578 | 2018 |
| 35. | Yu, Li-Rong ; Cao, Zhijun; Makhoul, Issam; Daniels, Jaclyn; Klimberg, Suzanne; Wei, Jeanne ; Bai, Jane; Li, Jinong; Lathrop, Julia; Beger, Richard ; Todorova, Valentina. Immune Response Proteins as Predictive biomarkers of Doxorubicin-induced Cardiotoxicity in Breast Cancer Patients. Exper Biol and Medicine, 2018; Feb;243(3):248-255. doi: 10.1177/1535370217746383. Epub 2017 Dec 9. PMID:29224368 | 2018 |
| 36. | Ameer FS , Zhang XM, Azhar G, and Wei JY. The Effect of Pegylated Liposomal Doxorubicin on Cellular Mitochondrial Function. J Pharm Clin Tox 2018; 6: 1099. | 2018 |
| 37. | Fathima S. Ameer , Xiaomin Zhang , Gohar Azhar and Jeanne Y. Wei* The Effect of Pegylated Liposomal Doxorubicin HCl on Cellular Mitochondrial Function Journal of Pharmacology and Clinical Toxicology, J Pharm Clin Tox 2018; 6: 1099. | 2018 |
| 38. | George M, McLawhorn JM, Azhar G, Jarrett D, Knight D. Advance Care Planning in Same-sex couples. CRIM, Vo1 1 (5) 2018 DOI: https://doi.org/10.5430/crim.v5n1p26 | 2018 |
| 40. | Mendiratta P. Losing a patient. J Mahatma Gandhi Inst Med Sci 2018;23:49-50 | 2018 |
| 41. | Kiaei M, Balasubramaniam M, Govind Kumar V, Shmookler Reis RJ,Moradi M, Varughese KI.ALS causing mutations in Profilin-1 protein alter its conformational dynamics: A computational approach to explain propensity for aggregation (Nature Sci Rep. 2018 Aug 30;8(1):13102. doi:10.1038) | 2018 |
| 42. | Janganati V, Ponder J, Balasubramaniam M, Jordan C, Crooks PA. Triazole derivatives of MMB are potent NFκB inhibitors andanticancer agents against both hematological and solid tumor cells (Eur J Med Chem. 2018 Aug10). | 2018 |
| 43. | Ralf Jäger, Chad M. Kerksick, Bill I. Campbell, Paul J. Cribb, Shawn D. Wells, Tim M. Skwiat, Martin Purpura, Tim N. Ziegenfuss, Arny A. Ferrando, Shawn M. Arent, Abbie E. Smith Ryan, Jeffrey R. Stout, Paul J. Arciero, Michael J. Ormsbee, Lem W. Taylor, Colin D. Wilborn, Doug S. Kalman, Richard B. Kreider, Darryn S. Willoughby, Leigh Breen, Jay R. Hoffman, Jose Antonio. International Society of Sports Nutrition Position Stand: Protein and Exercise. Journal of International Society of Sports Nutrition 2017 Jun 20; 14-20. | 2017 |
| 44. | Wardle, S.L., Macnaughton, L.S., McGlory, C., Witard, O.C., Whitfield, P.D., Ferrando, A.A., Hamilton, D.L., Moran, C.N., Tipton, K.D., Galloway, S.D.R. Human skeletal muscle responses to 6 days high-fat energy excess are associated with dietary n-3PUFA composition and muscle oxidative capacity. | |
| 45. | Chen, H.; Ferrando, A.A., White, M., Dunn, M., Ruiz-Margain, A., Kim, W., Duarte-Rojo, A. Cadence from physical fitness trackers for monitoring of home-based exercise intensity in end-stage liver disease. | |
| 46. | Ameer FS, Zhang XM, Azhar G, and Wei JY. Low glucose enhances metformin protection efficiency against doxorubicin induced cytotoxicity. J Biomed Sci. (submitted). | |
| 47. | Ayyadevara S, Ganne A, Hendrix RD, Balasubramaniam M, Reis RJS, Barger SW. Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease (In review Journal of NeuroscienceMethods) | |
| 48. | Kakraba S, Ayyadevara S, Balasubramaniam M*, Penthala NR, Ling L, Alla A, Bommagani S, Barger S, Griffin SW, Crooks PA, and Shmookler Reis RJ. Anti- inflammatory drug prevents and reverses protein aggregation in animal models of Alzheimer’s disease (In review Frontiers inNeurscience) | |
| 49. | Penthala NR, Ponder J, Balasubramaniam M, Morris E, Dachavaram S, Jordan CT, and Crooks PA. Synthesis and Investigation of In Vitro Antitumor Properties of Novel Benzyl and Phenethyl Melampomagnolide B Carbamates (Manuscript inp reparation) | |
| 50. | Ganne A, Hendrix R, Balasubramaniam M, Shmookler Reis RJ, Barger S, Griffin WS and Ayyadevara S.Western diet alters SERCA2 levels, PIP3-binding, and protein aggregation (Manuscript in preparation) | |
| 51. | Balasubramaniam M, Lakkaniga R, Rajagopalan P. Lead optimization of potent AKT inhitor 2-arylidene-4, 7-dimethyl indan-1-one. (In review Bioorganic and Medicinal Chemistry Letters) | |
| 52. | Bowroju SK, Penthala PA, Lopes EC, Balasubramaniam M, Straub KD, Guzman M, Crooks PA. Releasing Studies of the Signaling Molecule, Hydrogen Sulfide, by Antileukemic 1,2,4-Thiadiazolidine-3,5- Dione (TDZD) Derivatives in the presence of Thiols In Vitro, and their Antileukemic Activities (Manuscript inp reparation) | |
| 53. | Balasubramaniam M, Mainali N, Bowroju SK, Crooks PA, Robert JShoookler Reis, Srinivas Ayyadevara. Structural modeling of inactive (DFG “out”) conformation of GSK3β and mechanistic insights into TDZD binding (in review Nature Scientific Reports) | |
| 54. | Balasubramaniam M, Ganne A, Kiaei M, Shmookler Reis RJ, Varughese KI. Microsecond scale atomistic simulations reveals structural perturbations of various tubulin mutations leading to ALS(in preparation) | |
| 55. | Shmookler Reis RJ, Balasubramaniam M, Johnson J, Ayyadevara S. Protein aggregates” contain RNA and DNA: Co-translational entrapment of RNA, augmented by innocent-bystander inclusion of nucleic acids bound by misfolded proteins (manuscript in preparation) | |
| 56. | Balasubramaniam M, Lakkangia NR, Dera A, Fayi M, Abohashrh M, Ahmad I, Chandramoorhy H, Nalini G, Rajagopalan P. “FCX-146, a potent allosteric inhibitor of Akt Kinase in cancer cells: Lead optimization of the second-generation arylidene indanone scaffold” (in press Biotechnology and Applied Biochemistry) https://www.ncbi.nlm.gov/pubmed/?term=meenakshisundaram+balasubramaniam |