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  1. University of Arkansas for Medical Sciences
  2. Donald W. Reynolds Institute on Aging
  3. Research
  4. Aging Cardiovascular Research

Aging Cardiovascular Research

The Lyon Aging Cardiovascular Research Center (LACRC), partly supported by the Lyon Foundation, is dedicated to delineating the influence of adult advancing age on the heart and the vasculature. It aims to better understand the heart-brain connection and to seek new treatments with minimal side effects. As the director of the LACRC, Dr. Jeanne Wei’s major research interests include the effects of age on cardiovascular homeostasis, biology of aging, and mechanisms of cardiac and brain dysfunction

Jeanne Y. Wei, M.D., Ph.D.
Jeanne Y. Wei, M.D., Ph.D.
Website: Research Profile

Jeanne’s current major research interests include elucidating the effects of age on the brain, heart, vasculature and how cardiovascular changes affect cognition. She is interested in innovating cost effective care in frail elders, including ways to enhance cognitive resilience. She has received NIH research funding for over 35 years.

Gohar Azhar, M.D.
Gohar Azhar, M.D.
Website: Research Profile

Dr. Gohar Azhar’s aging cardiovascular research interests include investigating transcriptional control of the aging heart and physiological evaluation of stress responses of the aging cardiovascular system. Dr. Azhar was co-investigator on the NIH/NIA project titled “Transcription Regulation in the Aging Heart”.  She is also P.l. on an STTR, titled, “Nutritional Therapy in Elderly with Heart Failure”, phase I on which was recently completed.  In addition, she is collaborating on grants with investigators within the RIOA, across campus and at the Nutrition Center at the Arkansas Children’s hospital.

Xiaomin Zhang, M.D., Ph.D.
Website: Research Profile

Dr. Xiaomin Zhang is experienced in molecular biology, transgenesis and the genetic aspects of disease and aging. Dr. Zhang’s main research interests include the transcriptional regulation of gene expression during aging and senescence, and the mechanisms underlying age-related changes in the heart and skeletal muscle. He is also interested in using molecular biology approaches to generate mouse models that resemble certain aspects of aging, and using these models to enhance our understanding the mechanism of aging and senescence.

Donald W. Reynolds Institute on Aging LogoDonald W. Reynolds Institute on AgingDonald W. Reynolds Institute on Aging
Mailing Address: 4301 West Markham Street, Little Rock, AR 72205
Phone: (501) 686-7000
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